Firefighters are currently tackling a blaze at a property in Portadown this morning.
Crews are on the scene on Watson Street, which is currently closed as a result.
Police have advised road users and pedestrians to avoid the area altogether.
A Northern Ireland Fire & Rescue Service (NIFRS) Spokesperson said: “At 07:06am, NIFRS we were mobilised to a house fire at Watson Street, Portadown.
“Six fire appliances and an aerial appliance were mobilised from Lurgan, Portadown, Armagh, Banbridge, Dromore and Belfast.
“Three causalities are currently being treated for smoke inhalation. Firefighters are using breathing apparatus and water jets to extinguish the fire.
“The incident is ongoing. We would ask the public to avoid the area if possible.”
Please seek alternate routes for your journey.